The spectrum of disease manifestations is broad, ranging from silent infection to fulminant, malaria-like illness that can cause severe hemolysis — the destruction of red blood cells — and, in some cases, death. Babesia infections therefore range from almost asymptomatic to severe. The specific laboratory diagnosis of Babesia infection is performed through morphological examination of (Giemsa-stained) blood smears, serology, and, with variable success, DNA testing (PCR). Babesia infection causes alterations (protrusions and perforations) on the surface of red blood cells, and the pathogen itself can be identified inside the cells [1][3][4]. High-level infection can be detected through simple microscopic blood examination; in certain confirmed cases, the parasite infected a large proportion of red blood cells [4]. In general cases, concentration of infected red blood cells is required — for example, using the DualDur co-infection preparation method. According to the recommendation of the U.S. Centers for Disease Control and Prevention (CDC), babesiosis is primarily diagnosed through microscopic examination of the blood [5].